LIPOXOL MED
LIPOXOL MED grades are widely used excipients in a variety of pharmaceutical preparations. The liquid LIPOXOL MED grades are used as solvents, solubilizers, and viscosity regulators in liquid pharmaceutical formulations. Solid grades are used as a suppository base and act as binder and plasticizer for tablets. Mixtures of liquid and solid LIPOXOL MED grades are used as ointment base, and LIPOXOL 3350 MED SP and LIPOXOL 4000 MED SP serve as active pharmaceutical ingredients in laxatives.
| Features: | Temperature of melting and solidification range increases with increasing molecular weight; soluble in polar organic solvents like alcohols, benzene, glycerin, glycol or chloroform; good solubility in water; hygroscopic; moisturising; offers soft and readily dispersible ointment bases; enables liquid flow opposed to resorption; is non- toxic and non-irritant to skin shows cleansing and drying effect; provides conditioning effect after application; dissolves many active substances |
| Regional Availability: | Global |
| Regulatory & Compliance | Contact our sales team for region specific compliance & regulatory information. |
| Trade Name | LIPOXOL 300 MED | LIPOXOL 400 MED | LIPOXOL 600 MED |
|---|---|---|---|
| INCI Name: | PEG – 6 | PEG – 8 | PEG – 12 |
| Synonym: | PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide | PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide | PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide |
| CAS No.: | 25322-68-3 | 25322-68-3 | 25322-68-3 |
| Appearance at 20°C | Liquid | Liquid | Liquid |
| Colour number (APHA) (25% in d.i. water) (mg Pt/l) | ≤ 15 | ≤ 15 | ≤ 15 |
| Hydroxyl number (mg KOH/g) | 356 – 394 | 267 – 295 | 178 – 197 |
| Average molar mass (calc. from hydroxyl number) (g/mol) | 285 – 315 | 380 – 420 | 570 – 630 |
| Solidification range (°C) | – | – | 15 – 25 |
| pH (5% in d.i. water) | 4.5 – 7.5 | 4.5 – 7.5 | 4.5 – 7.5 |
| Water (% by mass) | ≤ 1.0 | ≤ 1.0 | ≤ 1.0 |
| dyn. Viscosity at 20°C (* 50% in water) (mPa s) | 80 – 105 | 105 – 130 | 15 – 20 |
| kinem. Viscosity at 98,9°C (mm²/s) | 5.4 – 6.4 | 6.8 – 8.0 | 9.9 – 11.3 |
| Ethylene and Diethylene glycol (% by mass) | ≤ 0.25 | ≤ 0.25 | ≤ 0.25 |
| Ethylene glycol (mg/kg) | ≤ 620 | ≤ 620 | ≤ 620 |
| Formaldehyde (mg/kg) | ≤ 30 | ≤ 30 | ≤ 30 |
| Dioxane (mg/kg) | ≤ 1 | ≤ 1 | ≤ 1 |
| Ethylene oxide (mg/kg) | ≤ 1 | ≤ 1 | ≤ 1 |
Trade Name
INCI Name:
LIPOXOL 300 MED
PEG – 6
LIPOXOL 400 MED
PEG – 8
LIPOXOL 600 MED
PEG – 12
Trade Name
Synonym:
LIPOXOL 300 MED
PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide
LIPOXOL 400 MED
PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide
LIPOXOL 600 MED
PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide
Trade Name
CAS No.:
LIPOXOL 300 MED
25322-68-3
LIPOXOL 400 MED
25322-68-3
LIPOXOL 600 MED
25322-68-3
Trade Name
Appearance at 20°C
LIPOXOL 300 MED
Liquid
LIPOXOL 400 MED
Liquid
LIPOXOL 600 MED
Liquid
Trade Name
Colour number (APHA) (25% in d.i. water) (mg Pt/l)
LIPOXOL 300 MED
≤ 15
LIPOXOL 400 MED
≤ 15
LIPOXOL 600 MED
≤ 15
Trade Name
Hydroxyl number (mg KOH/g)
LIPOXOL 300 MED
356 – 394
LIPOXOL 400 MED
267 – 295
LIPOXOL 600 MED
178 – 197
Trade Name
Average molar mass (calc. from hydroxyl number) (g/mol)
LIPOXOL 300 MED
285 – 315
LIPOXOL 400 MED
380 – 420
LIPOXOL 600 MED
570 – 630
Trade Name
Solidification range (°C)
LIPOXOL 300 MED
–
LIPOXOL 400 MED
–
LIPOXOL 600 MED
15 – 25
Trade Name
pH (5% in d.i. water)
LIPOXOL 300 MED
4.5 – 7.5
LIPOXOL 400 MED
4.5 – 7.5
LIPOXOL 600 MED
4.5 – 7.5
Trade Name
Water (% by mass)
LIPOXOL 300 MED
≤ 1.0
LIPOXOL 400 MED
≤ 1.0
LIPOXOL 600 MED
≤ 1.0
Trade Name
dyn. Viscosity at 20°C (* 50% in water) (mPa s)
LIPOXOL 300 MED
80 – 105
LIPOXOL 400 MED
105 – 130
LIPOXOL 600 MED
15 – 20
Trade Name
kinem. Viscosity at 98,9°C (mm²/s)
LIPOXOL 300 MED
5.4 – 6.4
LIPOXOL 400 MED
6.8 – 8.0
LIPOXOL 600 MED
9.9 – 11.3
Trade Name
Ethylene and Diethylene glycol (% by mass)
LIPOXOL 300 MED
≤ 0.25
LIPOXOL 400 MED
≤ 0.25
LIPOXOL 600 MED
≤ 0.25
Trade Name
Ethylene glycol (mg/kg)
LIPOXOL 300 MED
≤ 620
LIPOXOL 400 MED
≤ 620
LIPOXOL 600 MED
≤ 620
Trade Name
Formaldehyde (mg/kg)
LIPOXOL 300 MED
≤ 30
LIPOXOL 400 MED
≤ 30
LIPOXOL 600 MED
≤ 30
Trade Name
Dioxane (mg/kg)
LIPOXOL 300 MED
≤ 1
LIPOXOL 400 MED
≤ 1
LIPOXOL 600 MED
≤ 1
Trade Name
Ethylene oxide (mg/kg)
LIPOXOL 300 MED
≤ 1
LIPOXOL 400 MED
≤ 1
LIPOXOL 600 MED
≤ 1
| Trade Name | LIPOXOL 1000 MED | LIPOXOL 1500 MED | LIPOXOL 3000 MED | LIPOXOL 3350 MED |
|---|---|---|---|---|
| INCI Name: | PEG – 20 | PEG – 32 | PEG – 60 | PEG – 75 |
| Synonym: | PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide | PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide | PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide | PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide |
| CAS No.: | 25322-68-3 | 25322-68-3 | 25322-68-3 | 25322-68-3 |
| Appearance at 20°C | Solid | Solid, flakes | Flakes, milled powder | Flakes, milled or sprayed powder |
| Colour number (APHA) (25% in d.i. water) (mg Pt/l) | ≤ 15 | ≤ 15 | ≤ 15 | ≤ 15 |
| Hydroxyl number (mg KOH/g) | 107 – 118 | 70 – 80 | 31 – 37 | 26 – 31 |
| Average molar mass (calc. from hydroxyl number) (g/mol) | 950 – 1050 | 1400 – 1600 | 2700 – 3300 | 3015 – 3620 |
| Solidification range (°C) | 35 – 40 | 42 – 48 | 50 – 56 | 53 – 57 |
| pH (5% in d.i. water) | 4.5 – 7.5 | 4.5 – 7.5 | 4.5 – 7.5 | 4.5 – 7.5 |
| Water (% by mass) | ≤ 1.0 | ≤ 1.0 | ≤ 1.0 | ≤ 1.0 |
| dyn. Viscosity at 20°C (* 50% in water) (mPa s) | 22 – 30 | 34 – 50 | 75 – 100 | 83 – 120 |
| kinem. Viscosity at 98,9°C (mm²/s) | 16.0 – 19.0 | 26 – 33 | 67 – 93 | 76 – 110 |
| Ethylene and Diethylene glycol (% by mass) | ≤ 0.25 | ≤ 0.25 | ≤ 0.25 | ≤ 0.25 |
| Ethylene glycol (mg/kg) | ≤ 620 | ≤ 620 | ≤ 620 | ≤ 620 |
| Formaldehyde (mg/kg) | ≤ 30 | ≤ 30 | ≤ 30 | ≤ 30 |
| Dioxane (mg/kg) | ≤ 1 | ≤ 1 | ≤ 1 | ≤ 1 |
| Ethylene oxide (mg/kg) | ≤ 1 | ≤ 1 | ≤ 1 | ≤ 1 |
Trade Name
INCI Name:
LIPOXOL 1000 MED
PEG – 20
LIPOXOL 1500 MED
PEG – 32
LIPOXOL 3000 MED
PEG – 60
LIPOXOL 3350 MED
PEG – 75
Trade Name
Synonym:
LIPOXOL 1000 MED
PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide
LIPOXOL 1500 MED
PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide
LIPOXOL 3000 MED
PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide
LIPOXOL 3350 MED
PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide
Trade Name
CAS No.:
LIPOXOL 1000 MED
25322-68-3
LIPOXOL 1500 MED
25322-68-3
LIPOXOL 3000 MED
25322-68-3
LIPOXOL 3350 MED
25322-68-3
Trade Name
Appearance at 20°C
LIPOXOL 1000 MED
Solid
LIPOXOL 1500 MED
Solid, flakes
LIPOXOL 3000 MED
Flakes, milled powder
LIPOXOL 3350 MED
Flakes, milled or sprayed powder
Trade Name
Colour number (APHA) (25% in d.i. water) (mg Pt/l)
LIPOXOL 1000 MED
≤ 15
LIPOXOL 1500 MED
≤ 15
LIPOXOL 3000 MED
≤ 15
LIPOXOL 3350 MED
≤ 15
Trade Name
Hydroxyl number (mg KOH/g)
LIPOXOL 1000 MED
107 – 118
LIPOXOL 1500 MED
70 – 80
LIPOXOL 3000 MED
31 – 37
LIPOXOL 3350 MED
26 – 31
Trade Name
Average molar mass (calc. from hydroxyl number) (g/mol)
LIPOXOL 1000 MED
950 – 1050
LIPOXOL 1500 MED
1400 – 1600
LIPOXOL 3000 MED
2700 – 3300
LIPOXOL 3350 MED
3015 – 3620
Trade Name
Solidification range (°C)
LIPOXOL 1000 MED
35 – 40
LIPOXOL 1500 MED
42 – 48
LIPOXOL 3000 MED
50 – 56
LIPOXOL 3350 MED
53 – 57
Trade Name
pH (5% in d.i. water)
LIPOXOL 1000 MED
4.5 – 7.5
LIPOXOL 1500 MED
4.5 – 7.5
LIPOXOL 3000 MED
4.5 – 7.5
LIPOXOL 3350 MED
4.5 – 7.5
Trade Name
Water (% by mass)
LIPOXOL 1000 MED
≤ 1.0
LIPOXOL 1500 MED
≤ 1.0
LIPOXOL 3000 MED
≤ 1.0
LIPOXOL 3350 MED
≤ 1.0
Trade Name
dyn. Viscosity at 20°C (* 50% in water) (mPa s)
LIPOXOL 1000 MED
22 – 30
LIPOXOL 1500 MED
34 – 50
LIPOXOL 3000 MED
75 – 100
LIPOXOL 3350 MED
83 – 120
Trade Name
kinem. Viscosity at 98,9°C (mm²/s)
LIPOXOL 1000 MED
16.0 – 19.0
LIPOXOL 1500 MED
26 – 33
LIPOXOL 3000 MED
67 – 93
LIPOXOL 3350 MED
76 – 110
Trade Name
Ethylene and Diethylene glycol (% by mass)
LIPOXOL 1000 MED
≤ 0.25
LIPOXOL 1500 MED
≤ 0.25
LIPOXOL 3000 MED
≤ 0.25
LIPOXOL 3350 MED
≤ 0.25
Trade Name
Ethylene glycol (mg/kg)
LIPOXOL 1000 MED
≤ 620
LIPOXOL 1500 MED
≤ 620
LIPOXOL 3000 MED
≤ 620
LIPOXOL 3350 MED
≤ 620
Trade Name
Formaldehyde (mg/kg)
LIPOXOL 1000 MED
≤ 30
LIPOXOL 1500 MED
≤ 30
LIPOXOL 3000 MED
≤ 30
LIPOXOL 3350 MED
≤ 30
Trade Name
Dioxane (mg/kg)
LIPOXOL 1000 MED
≤ 1
LIPOXOL 1500 MED
≤ 1
LIPOXOL 3000 MED
≤ 1
LIPOXOL 3350 MED
≤ 1
Trade Name
Ethylene oxide (mg/kg)
LIPOXOL 1000 MED
≤ 1
LIPOXOL 1500 MED
≤ 1
LIPOXOL 3000 MED
≤ 1
LIPOXOL 3350 MED
≤ 1
| Trade Name | LIPOXOL 4000 MED | LIPOXOL 6000 MED |
|---|---|---|
| INCI Name: | PEG – 90 | PEG – 150 |
| Synonym: | PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide | PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide |
| CAS No.: | 25322-68-3 | 25322-68-3 |
| Appearance at 20°C | Flakes, milled or sprayed powder | Flakes, milled powder |
| Colour number (APHA) (25% in d.i. water) (mg Pt/l) | ≤ 15 | ≤ 15 |
| Hydroxyl number (mg KOH/g) | 17 – 21 | – |
| Average molar mass (calc. from hydroxyl number) (g/mol) | 3600 – 4400 | 5400 – 6600 |
| Solidification range (°C) | 53 – 58 | 55 – 61 |
| pH (5% in d.i. water) | 4.5 – 7.5 | 4.5 – 7.5 |
| Water (% by mass) | ≤ 1.0 | ≤ 1.0 |
| dyn. Viscosity at 20°C (* 50% in water) (mPa s) | 110 – 170 | 200 – 270 |
| kinem. Viscosity at 98,9°C (mm²/s) | 110 – 158 | 250 – 390 |
| Ethylene and Diethylene glycol (% by mass) | ≤ 0.25 | ≤ 0.25 |
| Ethylene glycol (mg/kg) | ≤ 620 | ≤ 620 |
| Formaldehyde (mg/kg) | ≤ 30 | ≤ 30 |
| Dioxane (mg/kg) | ≤ 1 | ≤ 1 |
| Ethylene oxide (mg/kg) | ≤ 1 | ≤ 1 |
Trade Name
INCI Name:
LIPOXOL 4000 MED
PEG – 90
LIPOXOL 6000 MED
PEG – 150
Trade Name
Synonym:
LIPOXOL 4000 MED
PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide
LIPOXOL 6000 MED
PEG, Macrogol, α-Hydro-ω-hydroxypoly-(oxy-1.2-ethynediyl), Polyoxyethylene glycol, Polyethylene oxide
Trade Name
CAS No.:
LIPOXOL 4000 MED
25322-68-3
LIPOXOL 6000 MED
25322-68-3
Trade Name
Appearance at 20°C
LIPOXOL 4000 MED
Flakes, milled or sprayed powder
LIPOXOL 6000 MED
Flakes, milled powder
Trade Name
Colour number (APHA) (25% in d.i. water) (mg Pt/l)
LIPOXOL 4000 MED
≤ 15
LIPOXOL 6000 MED
≤ 15
Trade Name
Hydroxyl number (mg KOH/g)
LIPOXOL 4000 MED
17 – 21
LIPOXOL 6000 MED
–
Trade Name
Average molar mass (calc. from hydroxyl number) (g/mol)
LIPOXOL 4000 MED
3600 – 4400
LIPOXOL 6000 MED
5400 – 6600
Trade Name
Solidification range (°C)
LIPOXOL 4000 MED
53 – 58
LIPOXOL 6000 MED
55 – 61
Trade Name
pH (5% in d.i. water)
LIPOXOL 4000 MED
4.5 – 7.5
LIPOXOL 6000 MED
4.5 – 7.5
Trade Name
Water (% by mass)
LIPOXOL 4000 MED
≤ 1.0
LIPOXOL 6000 MED
≤ 1.0
Trade Name
dyn. Viscosity at 20°C (* 50% in water) (mPa s)
LIPOXOL 4000 MED
110 – 170
LIPOXOL 6000 MED
200 – 270
Trade Name
kinem. Viscosity at 98,9°C (mm²/s)
LIPOXOL 4000 MED
110 – 158
LIPOXOL 6000 MED
250 – 390
Trade Name
Ethylene and Diethylene glycol (% by mass)
LIPOXOL 4000 MED
≤ 0.25
LIPOXOL 6000 MED
≤ 0.25
Trade Name
Ethylene glycol (mg/kg)
LIPOXOL 4000 MED
≤ 620
LIPOXOL 6000 MED
≤ 620
Trade Name
Formaldehyde (mg/kg)
LIPOXOL 4000 MED
≤ 30
LIPOXOL 6000 MED
≤ 30
Trade Name
Dioxane (mg/kg)
LIPOXOL 4000 MED
≤ 1
LIPOXOL 6000 MED
≤ 1
Trade Name
Ethylene oxide (mg/kg)
LIPOXOL 4000 MED
≤ 1
LIPOXOL 6000 MED
≤ 1
